Cholestasis in patients with Cockayne syndrome and suggested modified criteria for clinical diagnosis

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Cholestasis in patients with Cockayne syndrome and suggested modified criteria for clinical diagnosis

BACKGROUND Cockayne syndrome is a rare autosomal recessive neurodegenerative disease characterized by low-to-normal birth weight; growth failure; brain dysmyelination with calcium deposits, cutaneous photosensitivity; pigmentary retinopathy, cataract, and sensorineural hearing loss. To the best of our knowledge, cholestatic liver disease was not previously reported in these patients. AIM To h...

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Cockayne syndrome in three sisters with varying clinical presentation.

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ژورنال

عنوان ژورنال: Orphanet Journal of Rare Diseases

سال: 2011

ISSN: 1750-1172

DOI: 10.1186/1750-1172-6-13